Technical Data

041166
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Gene ID
4919
Gene #
ROR1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ROR1 (ROR1, NTRKR1, Tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1)
ROR1, NTRKR1, Tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1

ROR1 is a receptor protein tyrosine kinase whose cellular role has not been determined. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Studies of a similar protein in mouse suggest that this protein may interact with another receptor protein tyrosine kinase and may be involved in skeletal and cardiac development.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, and ELISA. Other applications not tested.
Recommended Dilution
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Requires HIER using sodium citrate buffer pH6.0 prior to staining. Indirect Flow Cytometry: 1:25 Optimal dilution to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Recombinant protein mapping to a fragment of residues within amino acids 112-39 human ROR1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Specificity
Recognizes human ROR1. Species Crossreactivity: mouse.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Nomi, M., et al., Mol. Cell. Biol. 21(24):8329-8335 (2001). 2. Reddy, U.R., et al., Genomics 41(2):283-285 (1997). 3. Reddy, U.R., et al., Oncogene 13(7):1555-1559 (1996). 4. Masiakowski, P., et al., J. Biol. Chem. 267(36):26181-26190 (1992).
USBio References
No references available
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