041188
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_009035.3Gene ID
4736Gene #
RPL10AShipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-RPL10A, NT (RPL10A, NEDD6, 60S ribosomal protein L10a, CSA-19, Neural precursor cell expressed developmentally down-regulated protein 6)
RPL10A, NEDD6, 60S ribosomal protein L10a, CSA-19, Neural precursor cell expressed developmentally down-regulated protein 6
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq].
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
RPL10A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human RPL10A.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Andersen, J.S., et al. Nature 433(7021):77-83(2005)|Kapp, L.D., et al. Annu. Rev. Biochem. 73, 657-704 (2004) :|Mungall, A.J., et al. Nature 425(6960):805-811(2003)|Mazumder, B., et al. Cell 115(2):187-198(2003)|Odintsova, T.I., et al. J. Protein Chem. 22(3):249-258(2003)USBio References
No references available