041234
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_001020241.1; NP_005608.1Gene ID
6208Gene #
RPS14Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-RPS14, CT (RPS14, 40S ribosomal protein S14)
RPS14, 40S ribosomal protein S14
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
RPS14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-147 amino acids from the C-terminal region of human RPS14.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Oliva, E.N., et al. Eur. J. Haematol. 85(3):231-235(2010)|Borze, I., et al. Cancer Genet. Cytogenet. 197(2):166-173(2010)|Quarello, P., et al. Haematologica 95(2):206-213(2010)|Valencia, A., et al. Blood 112 (3), 918 (2008) :|Ebert, B.L., et al. Nature 451(7176):335-339(2008)USBio References
No references available