Technical Data

041392
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_056289.2
Gene ID
25939
Gene #
SAMHD1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SAMHD1, ID (SAMHD1, MOP5, SAM domain and HD domain-containing protein 1, Dendritic cell-derived IFNG-induced protein, Monocyte protein 5)
SAMHD1, MOP5, SAM domain and HD domain-containing protein 1, Dendritic cell-derived IFNG-induced protein, Monocyte protein 5

This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq].

Applications
Suitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 204-230 in the central region of human SAMHD1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human SAMHD1.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Tomkova, H., et al. Eur J Dermatol 20(3):411-413(2010). 2. Dale, R.C., et al. Am. J. Med. Genet. A 152A (4), 938-942 (2010). 3. Davila, S., et al. Genes Immun. 11(3):232-238(2010). 4. Rice, G.I., et al. Nat. Genet. 41(7):829-832(2009). 5. Liao, W., et al. Proteomics 8(13):2640-2650(2008)
USBio References
No references available
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