Technical Data

041468
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_002969.2
Gene ID
6339
Gene #
SCNN1D
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SCNN1D, NT (SCNN1D, DNACH, Amiloride-sensitive sodium channel subunit delta, Delta-NaCH, Epithelial Na(+) channel subunit delta, Nonvoltage-gated sodium channel 1 subunit delta, SCNED)
SCNN1D, DNACH, Amiloride-sensitive sodium channel subunit delta, Delta-NaCH, Epithelial Na(+) channel subunit delta, Nonvoltage-gated sodium channel 1 subunit delta, SCNED

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SCNN1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-189 amino acids from the N-terminal region of human SCNN1D.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Wesch, D., et al. Am. J. Physiol., Cell Physiol. 299 (4), C779-C790 (2010) :|Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Bangel-Ruland, N., et al. Am. J. Respir. Cell Mol. Biol. 42(4):498-505(2010)|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)|Haerteis, S., et al. J. Biol. Chem. 284(42):29024-29040(2009)
USBio References
No references available
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