Technical Data

041624-APC
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Conjugate
APC
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA WB
Crossreactivity
Hu
Accession #
NP_003005.2
Gene ID
6424
Gene #
SFRP4
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Rabbit Anti-SFRP4, CT (SFRP4, FRPHE, Secreted frizzled-related protein 4, Frizzled protein, human endometrium) (APC)
SFRP4, FRPHE, Secreted frizzled-related protein 4, Frizzled protein, human endometrium

Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression.

Applications
Suitable for use in Western Blot, Flow Cytometry (Not Tested) and FLISA. Other applications have not been tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 318-346 in the c-terminal region of human SFRP4.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human SFRP4.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Lee, D.Y., et al. Menopause 17(5):1064-1070 (2010). 2. Kohno, H., et al. Oncol. Rep. 24(2):423-431 (2010). 3. Frank, B., et al. Carcinogenesis 31(8):1381-1386 (2010). 4. Huang, D., et al. J. Cancer Res. Clin. Oncol. 136(3):395-401 (2010). 5. Hirata, H., et al. Cancer 115(19):4488-4503(2009)
USBio References
No references available
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