Technical Data

041632-APC
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Conjugate
APC
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA WB
Crossreactivity
Hu Mo
Accession #
NP_115285.1
Gene ID
10929
Gene #
SRSF8
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Rabbit Anti-SFRS2B, NT (SRSF8, SFRS2B, SRP46, Serine/arginine-rich splicing factor 8, Pre-mRNA-splicing factor SRP46, Splicing factor, arginine/serine-rich 2B) (APC)
SRSF8, SFRS2B, SRP46, Serine/arginine-rich splicing factor 8, Pre-mRNA-splicing factor SRP46, Splicing factor, arginine/serine-rich 2B

The SR (serine/arginine-rich) family contains a number of phosphoproteins that function as essential and alternative splicing factors. The SR family of proteins is characterized by the presence of a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The protein encoded by this gene is a member of the SR family and functions as an essential splicing factor in vitro. This gene is thought to be an expressed PR264/SC35 retropseudogene.

Applications
Suitable for use in Western Blot and FLISA. Other applications not tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 45-73 in the N-terminal region of human SFRS2B.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human SFRS2B. Species Crossreactivity: mouse.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Manley, J.L., et al. Genes Dev. 24(11):1073-1074(2010). 2. Lareau, L.F., et al. Nature 446(7138):926-929(2007). 3. Olsen, J.V., et al. Cell 127(3):635-648(2006). 4. Li, J., et al. Mol. Cell. Biol. 23(21):7437-7447(2003). 5. Grottke, C., et al. Int. J. Cancer 88(4):535-546(2000).
USBio References
No references available
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