Technical Data

041652
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu Mo
Gene ID
84251
Gene #
SGIP1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SGIP1, NT (SGIP1, SH3-containing GRB2-like protein 3-interacting protein 1, Endophilin-3-interacting protein)
SGIP1, SH3-containing GRB2-like protein 3-interacting protein 1, Endophilin-3-interacting protein

SGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3; MIM 603362) (Trevaskis et al., 2005 [PubMed 15919751] and Uezu et al., 2007 [PubMed 17626015]).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SGIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human SGIP1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Luke, M.M., et al. Stroke 40(2):363-368(2009)|Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008)|Uezu, A., et al. J. Biol. Chem. 282(36):26481-26489(2007)|Trevaskis, J., et al. Endocrinology 146(9):3757-3764(2005)|Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
USBio References
No references available
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