041691
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_055336.1Gene ID
23677Gene #
SH3BP4Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-SH3BP4, ID (SH3BP4, BOG25, EHB10, TTP, SH3 domain-binding protein 4, EH-binding protein 10, Transferrin receptor-trafficking protein)
SH3BP4, BOG25, EHB10, TTP, SH3 domain-binding protein 4, EH-binding protein 10, Transferrin receptor-trafficking protein
This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor.
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SH3BP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-429 amino acids from the Central region of human SH3BP4.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Sebastiani, P., et al. Science (2010) In press :|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Thalappilly, S., et al. Proteomics 8(15):3071-3081(2008)|Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :|Olsen, J.V., et al. Cell 127(3):635-648(2006)USBio References
No references available