SIRPB2, CT (SIRPB2, PTPN1L, PTPNS1L3, Signal-regulatory protein beta-2, Protein tyrosine phosphatase non-receptor type substrate 1-like 3, Protein tyrosine phosphatase non-receptor type substrate protein)

041754

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Isotype

IgG

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Accession #

NP_001116434.1

Gene ID

284759

Gene #

SIRPB2

Shipping Temp

Blue Ice

Storage Temp

-20°C

Rabbit Anti-SIRPB2, CT (SIRPB2, PTPN1L, PTPNS1L3, Signal-regulatory protein beta-2, Protein tyrosine phosphatase non-receptor type substrate 1-like 3, Protein tyrosine phosphatase non-receptor type substrate protein)

SIRPB2, PTPN1L, PTPNS1L3, Signal-regulatory protein beta-2, Protein tyrosine phosphatase non-receptor type substrate 1-like 3, Protein tyrosine phosphatase non-receptor type substrate protein

Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.

Applications

Suitable for use in Western Blot, ELISA

Recommended Dilution

ELISA: 1:1,000 Western Blot: 1:100-500

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

SIRPB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-255 amino acids from the C-terminal region of human SIRPB2.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A affinity chromatography.

Specificity

Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References

Nyati, M.K., et al. Cancer Res. 66(24):11554-11559(2006)|van den Berg, T.K., et al. J. Immunol. 175(12):7788-7789(2005)|Chen, J., et al. Proc. Natl. Acad. Sci. U.S.A. 99(19):12257-12262(2002)

USBio References

No references available

Technical Data

041754

Clone Type

Host

Source

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

Rabbit Anti-SIRPB2, CT (SIRPB2, PTPN1L, PTPNS1L3, Signal-regulatory protein beta-2, Protein tyrosine phosphatase non-receptor type substrate 1-like 3, Protein tyrosine phosphatase non-receptor type substrate protein)

SIRPB2, PTPN1L, PTPNS1L3, Signal-regulatory protein beta-2, Protein tyrosine phosphatase non-receptor type substrate 1-like 3, Protein tyrosine phosphatase non-receptor type substrate protein

References

USBio References