Technical Data

041767
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_787071.2
Gene ID
147912
Gene #
SIX5
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SIX5, ID (SIX5, DMAHP, Homeobox protein SIX5, DM locus-associated homeodomain protein, Sine oculis homeobox homolog 5)
SIX5, DMAHP, Homeobox protein SIX5, DM locus-associated homeodomain protein, Sine oculis homeobox homolog 5

The protein encoded by this gene is a homeodomain-containing transcription factor that appears to function in the regulation of organogenesis. This gene is located downstream of the dystrophia myotonica-protein kinase gene. Mutations in this gene are a cause of branchiootorenal syndrome type 2.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SIX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-294 amino acids from the Central region of human SIX5.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)|Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)|Hoskins, B.E., et al. Am. J. Hum. Genet. 80(4):800-804(2007)|Sato, S., et al. Hum. Mol. Genet. 11(9):1045-1058(2002)|Fougerousse, F., et al. J. Muscle Res. Cell. Motil. 23(3):255-264(2002)
USBio References
No references available
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