041823-FITC
Clone Type
PolyclonalHost
RabbitSource
HumanConjugate
FITCIsotype
IgGGrade
Affinity PurifiedApplications
FLISA IHC WBCrossreactivity
HuAccession #
NP_003048.1; NP_694857.1Gene ID
6580Gene #
SLC22A1Shipping Temp
Blue IceStorage Temp
-20°CNotes
Preservative Free
Rabbit Anti-SLC22A1, CT (SLC22A1, OCT1, Solute carrier family 22 member 1, Organic cation transporter 1) (FITC)
SLC22A1, OCT1, Solute carrier family 22 member 1, Organic cation transporter 1
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq].
Applications
Suitable for use in Western Blot, Immunohistochemistry and FLISA. Other applications not tested.
Recommended Dilutions
Immunohistochemistry: Formalin-fixed, paraffin-embedded sections Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 511-539 in the C-terminal region of human SLC22A1
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Purity
Purified by Protein A and peptide affinity chromatography
Specificity
Recognizes human SLC22A1
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Takahashi, N., et al. J. Hum. Genet. 55(11):731-737(2010). 2. Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010). 3. Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010). 4. Gambineri, A., et al. J. Clin. Endocrinol. Metab. 95 (10), E204-E208 (2010). 5. Becker, M.L., et al. Neurogenetics (2010)USBio References
No references available