Technical Data

041888
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_060814.4
Gene ID
55315
Gene #
SLC29A3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SLC29A3, NT (SLC29A3, ENT3, Equilibrative nucleoside transporter 3, Solute carrier family 29 member 3)
SLC29A3, ENT3, Equilibrative nucleoside transporter 3, Solute carrier family 29 member 3

This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SLC29A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the N-terminal region of human SLC29A3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Gass, N., et al. J Affect Disord 126 (1-2), 134-139 (2010) :|Kang, N., et al. J. Biol. Chem. 285(36):28343-28352(2010)|Li, X., et al. Zhongguo Fei Ai Za Zhi 13(5):458-463(2010)|Priya, T.P., et al. Br. J. Dermatol. 162(5):1132-1134(2010)|Cliffe, S.T., et al. Hum. Mol. Genet. 18(12):2257-2265(2009)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net