Technical Data

041958
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_003606.3; Q9Y6M7
Gene ID
9497
Gene #
SLC4A7
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SLC4A7, CT (SLC4A7, BT, NBC2, NBC2B, NBC3, SBC2, SLC4A6, Sodium bicarbonate cotransporter 3, Sodium bicarbonate cotransporter 2, Sodium bicarbonate cotransporter 2b, Solute carrier family 4 member 7)
SLC4A7, BT, NBC2, NBC2B, NBC3, SBC2, SLC4A6, Sodium bicarbonate cotransporter 3, Sodium bicarbonate cotransporter 2, Sodium bicarbonate cotransporter 2b, Solute carrier family 4 member 7

SLC4A7 regulates intracellular pH and may also play a role in bicarbonate salvage in secretory epithelia. Additionally, SLC4A7 may also have associated sodium channel activity.

Applications
Suitable for use in Immunohistochemistry, Western Blot and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1186-1214 in the C-terminal region of human SLC4A7.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human SLC4A7.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Odefrey, F., et al. Cancer Res. 70(4):1449-1458(2010) 2. Ahmed, S., et al. Nat. Genet. 41(5):585-590(2009) 3. Ishiguro, H., et al. Addiction 102(8):1320-1325(2007) 4. Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) 5. Olsen, J.V., et al. Cell 127(3):635-648(2006)
USBio References
No references available
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