Technical Data

042097
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_003080.2
Gene ID
6625
Gene #
SNRNP70
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SNRNP70, ID (SNRNP70, RNPU1Z, RPU1, SNRP70, U1AP1, U1 small nuclear ribonucleoprotein 70kD)
SNRNP70, RNPU1Z, RPU1, SNRP70, U1AP1, U1 small nuclear ribonucleoprotein 70kD

SNRNP70 mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.

Applications
Suitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Optimal working dilutions to be determined by researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 194-223 from the central region of human SNRNP70.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human SNRNP70.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Spiluttini, B., et al. J. Cell. Sci. 123 (PT 12):2085-2093 (2010), 2. Tzang, B.S., et al. J. Biomed. Sci. 17:40 (2010), 3. Parente Costa, L., et al. J. Autoimmun. 33(2):121-124(2009), 4. Hernandez, H., et al. PLoS ONE 4(9):E7202 (2009), 5. Palafox Sanchez, C.A., et al. Arthritis Res. Ther. 11(1):R27 (2009)
USBio References
No references available
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