Technical Data

042170
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_005625.2
Gene ID
6658
Gene #
SOX3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SOX3, ID (SOX3, Transcription factor SOX-3)
SOX3, Transcription factor SOX-3

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SOX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-204 amino acids from the Central region of human SOX3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Dateki, S., et al. J. Clin. Endocrinol. Metab. 95(8):4043-4047(2010)|Sato, Y., et al. Mol. Cell. Biochem. 337 (1-2), 267-275 (2010) :|Mojsin, M., et al. Biochem. J. 425(1):107-116(2010)|Bleyl, S.B., et al. Am. J. Med. Genet. A 143A (23), 2785-2795 (2007) :|Krstic, A., et al. Arch. Biochem. Biophys. 467(2):163-173(2007)
USBio References
No references available
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