Technical Data

042184
Clone Type
Polyclonal
Host
Rabbit
Source
Mouse
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Mo
Accession #
NP_003101.3
Gene ID
6668
Gene #
SP2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SP2, CT (SP2, KIAA0048, Transcription factor Sp2)
SP2, KIAA0048, Transcription factor Sp2

This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 497-527 amino acids from the C-terminal region of human SP2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Ito, H., et al. Biochim. Biophys. Acta 1789 (11-12), 681-690 (2009) :|Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :|Letourneur, M., et al. Mol. Immunol. 46 (11-12), 2151-2160 (2009) :|Sun, J.M., et al. J. Biol. Chem. 282(45):33227-33236(2007)|Das, A., et al. J. Biol. Chem. 281(51):39105-39113(2006)
USBio References
No references available
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