Technical Data

042189
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu Mo
Accession #
NP_874359.2
Gene ID
221833
Gene #
SP8
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SP8, CT (SP8, Transcription factor Sp8, Specificity protein 8)
SP8, Transcription factor Sp8, Specificity protein 8

Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity).

Applications
Suitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after reciept. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 386-415 in the C-terminal region of human SP8, UniProt Accession #Q81XZ3. Species sequence homology: chicken, xenopus, zebrafish
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human SP8. Species Crossreactivity: mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Lee, M.T., et al. Mol. Psychiatry (2010) In press : 2. Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) : 3. Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) : 4. Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009) 5. Milona, M.A., et al. BMC Genomics 5 (1), 86 (2004) :
USBio References
No references available
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