Technical Data

042236
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
O43278; NP_857593.1; NP_001027539.1
Gene ID
6692
Gene #
SPINT1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SPINT1, ID (SPINT1, HAI1, Kunitz-type protease inhibitor 1, Hepatocyte growth factor activator inhibitor type 1)
SPINT1, HAI1, Kunitz-type protease inhibitor 1, Hepatocyte growth factor activator inhibitor type 1

The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SPINT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-207 amino acids from the Central region of human SPINT1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Chen, Y.W., et al. J. Biol. Chem. 285(41):31755-31762(2010)|Kauppinen, J.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(9):2133-2142(2010)|Nakamura, K., et al. Int. J. Oncol. 35(2):239-248(2009)|Wang, J.K., et al. Am. J. Physiol., Cell Physiol. 297 (2), C459-C470 (2009) :|Cheng, H., et al. Cancer Res. 69(5):1828-1835(2009)
USBio References
No references available
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