Technical Data

042329
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Accession #
NP_003136.1
Gene ID
6746
Gene #
SSR2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SSR2, CT (SSR2, TRAPB, Translocon-associated protein subunit beta, Signal sequence receptor subunit beta)
SSR2, TRAPB, Translocon-associated protein subunit beta, Signal sequence receptor subunit beta

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq].

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 154-183 in the C-terminal region of human SSR2, UniProt Accession #P43308. Species sequence homology: bovine
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human SSR2.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : 2. Sikorska, M., et al. J. Neurosci. Res. 86(8):1680-1693(2008) 3. Zhang, H., et al. Nat. Biotechnol. 21(6):660-666(2003) 4. Wang, L., et al. FEBS Lett. 457(3):316-322(1999) 5. Dodson, G., et al. Curr. Opin. Struct. Biol. 8(2):189-194(1998)
USBio References
No references available
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