Technical Data

042342
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
O60225; NP_066295.3
Gene ID
6758
Gene #
SSX5
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-SSX5, NT (SSX5, Protein SSX5)
SSX5, Protein SSX5

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SSX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SSX5.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Wu, L.Q., et al. Life Sci. 79(8):744-748(2006)|Ross, M.T., et al. Nature 434(7031):325-337(2005)|Gure, A.O., et al. Int. J. Cancer 101(5):448-453(2002)|de Bruijn, D.R., et al. Genes Chromosomes Cancer 34(3):285-298(2002)|Chen, C.H., et al. Cancer Lett. 164(2):189-195(2001)
USBio References
No references available
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