Technical Data

042426
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_000342.2
Gene ID
412
Gene #
STS
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-STS, CT (STS, ARSC1, Steryl-sulfatase, Arylsulfatase C, Steroid sulfatase, Steryl-sulfate sulfohydrolase)
STS, ARSC1, Steryl-sulfatase, Arylsulfatase C, Steroid sulfatase, Steryl-sulfate sulfohydrolase

The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI).

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
STS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-517 amino acids from the C-terminal region of human STS.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Chanplakorn, N., et al. Breast Cancer Res. Treat. 120(3):639-648(2010)|Gruber, R., et al. J. Dermatol. Sci. 58(1):72-75(2010)|Canueto, J., et al. J Eur Acad Dermatol Venereol (2010) In press :|Li, J., et al. Breast Cancer Res. 12 (2), R19 (2010) :|Chakrabarti, B., et al. Autism Res 2(3):157-177(2009)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net