Technical Data

042432
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC WB
Crossreactivity
Hu
Accession #
O14662; NP_001128245.1; NP_001001433.1; NP_003754.2
Gene ID
8675
Gene #
STX16
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-STX16, CT (STX16, Syntaxin-16)
STX16, Syntaxin-16

This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications
Suitable for use in Western Blot, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
STX16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-282 amino acids from the C-terminal region of human STX16.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Song, S.J., et al. Cancer Res. 69(22):8540-8544(2009)|Ganley, I.G., et al. J. Cell Biol. 180(1):159-172(2008)|Chua, C.E., et al. Mol. Membr. Biol. 25(1):35-45(2008)|Amessou, M., et al. J. Cell. Sci. 120 (PT 8), 1457-1468 (2007) :|Linglart, A., et al. Am. J. Hum. Genet. 76(5):804-814(2005)
USBio References
No references available
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