Technical Data

042630
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu Mo
Accession #
NP_060891.3
Gene ID
55357
Gene #
TBC1D2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TBC1D2, ID (TBC1D2, PARIS1, PP8997, TBC1D2A, TBC1 domain family member 2A, Armus, Prostate antigen recognized and identified by SEREX 1)
TBC1D2, PARIS1, PP8997, TBC1D2A, TBC1 domain family member 2A, Armus, Prostate antigen recognized and identified by SEREX 1

TBC1D2 acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivativation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TBC1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-465 amino acids from the Central region of human TBC1D2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Letra, A., et al. Am. J. Med. Genet. A 152A (7), 1701-1710 (2010) :|Ishibashi, K., et al. Genes Cells 14(1):41-52(2009)|Olsen, J.V., et al. Cell 127(3):635-648(2006)|Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)|Zhou, Y., et al. Biochem. Biophys. Res. Commun. 290(2):830-838(2002)
USBio References
No references available
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