Technical Data

042645
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001272.2
Gene ID
1155
Gene #
TBCB
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TBCB, NT (TBCB, CG22, CKAP1, Tubulin-folding cofactor B, Cytoskeleton-associated protein 1, Cytoskeleton-associated protein CKAPI, Tubulin-specific chaperone B)
TBCB, CG22, CKAP1, Tubulin-folding cofactor B, Cytoskeleton-associated protein 1, Cytoskeleton-associated protein CKAPI, Tubulin-specific chaperone B

TBCB binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TBCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human TBCB.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Bailey, S.D., et al. Diabetes Care (2010) In press :|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)|Cleveland, D.W., et al. Hum. Mol. Genet. 18(8):1384-1394(2009)|Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)|Fanarraga, M.L., et al. Exp. Cell Res. 315(3):535-541(2009)
USBio References
No references available
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Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net