Technical Data

042720
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu Mo
Accession #
NP_055105.2
Gene ID
23424
Gene #
TDRD7
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TDRD7, CT (TDRD7, PCTAIRE2BP, Tudor domain-containing protein 7, PCTAIRE2-binding protein, Tudor repeat associator with PCTAIRE 2)
TDRD7, PCTAIRE2BP, Tudor domain-containing protein 7, PCTAIRE2-binding protein, Tudor repeat associator with PCTAIRE 2

TDRD7, also known as Tudor domain containing protein 7, is a component of chromatoid bodies in spermatids (named processing bodies or P-bodies in somatic cells). It is found in a mRNP complex together with TDRD1, TDRD6 and DDX4. It is also found in a complex with CABLES1, PCTK2 and PIWIL1. TDRD7 has been shown to interact with histone H3 tri-methylated at K9 in vitro.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TDRD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 807-835 amino acids from the C-terminal region of human TDRD7.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Lim, J., et al. Cell 125(4):801-814(2006)|Conte, N., et al. Oncogene 22(50):8102-8116(2003)|Lauffart, B., et al. Biochem. J. 363 (PT 1), 195-200 (2002) :|Yamochi, T., et al. Biochem. Biophys. Res. Commun. 286(5):1045-1050(2001)|Hirose, T., et al. Eur. J. Biochem. 267(7):2113-2121(2000)
USBio References
No references available
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