TFCP2L1is a transcriptional suppressor. It may suppress UBP1-mediated transcriptional activation. Modulates the placental expression of CYP11A1.
Applications
Suitable for use in FLISA, Western Blot and Immunohistochemisty. Other potential application, though not tested is Direct Flow Cytometry. Other applications not tested.
Recommended Dilutions
Immunohistochemistry: Formalin-fixed, paraffin-embedded sections Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 222-251 in the central region of human TFCP2L1
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Purity
Purified by Protein A and peptide affinity chromatography
Specificity
Recognizes human TFCP2L1. Species Crossreactivity: mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. To, S., et al. PLoS ONE 5 (7), E11702 (2010). 2. Henderson, Y.C., et al. DNA Cell Biol. 27(2):71-79 (2008). 3. Hillier, L.W., et al. Nature 434 (7034):724-731 (2005). 4. Huang, N., et al. Mol. Endocrinol. 19( 2):409-420 (2005). 5. Rodda, S., et al. J. Biol. Chem. 276 (5):3324-3332 (2001)
USBio References
No references available
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