Technical Data

042808
Clone Type
Polyclonal
Host
Rabbit
Source
Mouse
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Mo
Accession #
NP_001010923.1; NP_001158157.1
Gene ID
387357
Gene #
THEMIS
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-THEMIS, CT (THEMIS, C6orf190, C6orf207, Protein THEMIS, Thymocyte-expressed molecule involved in selection)
THEMIS, C6orf190, C6orf207, Protein THEMIS, Thymocyte-expressed molecule involved in selection

This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
THEMIS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 566-595 amino acids from the C-terminal region of human THEMIS.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)|Bhatti, P., et al. Radiat. Res. 173(2):214-224(2010)|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)|Patrick, M.S., et al. Proc. Natl. Acad. Sci. U.S.A. 106(38):16345-16350(2009)
USBio References
No references available
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