Technical Data

042851
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu Mo
Accession #
NP_003247.1
Gene ID
7079
Gene #
TIMP4
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TIMP4, ID (TIMP4, Metalloproteinase inhibitor 4, Tissue inhibitor of metalloproteinases 4)
TIMP4, Metalloproteinase inhibitor 4, Tissue inhibitor of metalloproteinases 4

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TIMP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-82 amino acids from the Central region of human TIMP4.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Nalpas, B., et al. Gut 59(8):1120-1126(2010)|Bailey, S.D., et al. Diabetes Care (2010) In press :|Wojciechowski, R., et al. Invest. Ophthalmol. Vis. Sci. (2010) In press :|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)|Liss, M., et al. Am. J. Pathol. 175(3):940-946(2009)
USBio References
No references available
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