Technical Data

043005
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_112200.2
Gene ID
81671
Gene #
TMEM49
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TMEM49, CT (VMP1, TDC1, TMEM49, Vacuole membrane protein 1, Transmembrane protein 49)
VMP1, TDC1, TMEM49, Vacuole membrane protein 1, Transmembrane protein 49

Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis (By similarity).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TMEM49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-406 amino acids from the C-terminal region of human TMEM49.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Pardo, R., et al. Pancreatology 10(1):19-26(2010)|Calvo-Garrido, J., et al. Mol. Biol. Cell 19(8):3442-3453(2008)|Fujita, S., et al. J. Mol. Biol. 378(3):492-504(2008)|Sauermann, M., et al. Oncogene 27(9):1320-1326(2008)|Ropolo, A., et al. J. Biol. Chem. 282(51):37124-37133(2007)
USBio References
No references available
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