043083
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E IHC WBCrossreactivity
HuAccession #
NP_006564.1; NP_001139117.1Gene ID
10673Gene #
TNFSF13BShipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-TNFSF13B, NT (TNFSF13B, BAFF, BLYS, TALL1, TNFSF20, ZTNF4, Tumor necrosis factor ligand superfamily member 13B, B lymphocyte stimulator, B Cell-activating factor, Dendritic cell-derived TNF-like molecule, TNF- and APOL-related leukocyte expressed ligand 1, CD257, Tumor necrosis factor ligand superfamily member 13b, membrane form, Tumor necrosis factor ligand superfamily member 13b, soluble form)
TNFSF13B, BAFF, BLYS, TALL1, TNFSF20, ZTNF4, Tumor necrosis factor ligand superfamily member 13B, B lymphocyte stimulator, B-cell-activating factor, Dendritic cell-derived TNF-like molecule, TNF- and APOL-related leukocyte expressed ligand 1, CD257, Tumor necrosis factor ligand superfamily member 13b, membrane form, Tumor necrosis factor ligand superfamily member 13b, soluble form
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells.
Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TNFSF13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human TNFSF13B.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Zhang, W., et al. Proc. Natl. Acad. Sci. U.S.A. 107(44):18956-18960(2010)|Molica, S., et al. Eur. J. Haematol. 85(4):314-320(2010)|Liu, J.Q., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 18(3):690-693(2010)|Onda, K., et al. Int. J. Hematol. 91(5):808-819(2010)|Hayashi, E.A., et al. J. Immunol. 184(9):4662-4672(2010)USBio References
No references available