Technical Data

043086
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_005083.2
Gene ID
8995
Gene #
TNFSF18
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TNFSF18, ID (TNFSF18, AITRL, GITRL, TL6, Tumor necrosis factor ligand superfamily member 18, Activation-inducible TNF-related ligand, Glucocorticoid-induced TNF-related ligand)
TNFSF18, AITRL, GITRL, TL6, Tumor necrosis factor ligand superfamily member 18, Activation-inducible TNF-related ligand, Glucocorticoid-induced TNF-related ligand

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TNFSF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-121 amino acids from the Central region of human TNFSF18.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Han, S., et al. Hum. Immunol. 71(7):727-730(2010)|Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)|Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)|Davila, S., et al. Genes Immun. 11(3):232-238(2010)
USBio References
No references available
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