Technical Data

043096
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E FC WB
Crossreactivity
Hu Mo
Accession #
NP_079511.1
Gene ID
80351
Gene #
TNKS2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-Tnks 2, CT (TNKS2, PARP5B, TANK2, TNKL, Tankyrase-2, ADP-ribosyltransferase diphtheria toxin-like 6, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein)
TNKS2, PARP5B, TANK2, TNKL, Tankyrase-2, ADP-ribosyltransferase diphtheria toxin-like 6, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein

Tnks 2 may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Tnks 2 has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.

Applications
Suitable for use in Western Blot, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Tnks 2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1134-1164 amino acids from the C-terminal region of human Tnks 2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Varadi, V., et al. Eur. J. Cancer 45(17):3008-3016(2009)|Shebzukhov, Y.V., et al. Cancer Immunol. Immunother. 57(6):871-881(2008)|Sidorova, N.N., et al. Biochemistry Mosc. 73(3):289-295(2008)
USBio References
No references available
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