Technical Data

043111
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Gene ID
3842
Gene #
TNPO1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TNPO1, NT (TNPO1, KPNB2, MIP1, TRN, Transportin-1, Importin beta-2, Karyopherin beta-2, M9 region interaction protein)
TNPO1, KPNB2, MIP1, TRN, Transportin-1, Importin beta-2, Karyopherin beta-2, M9 region interaction protein

TNPO1 comprises the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TNPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45~75 amino acids from the N-terminal region of human TNPO1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Fineberg, K., et al., Biochemistry 42(9):2625-2633 (2003).|Nelson, L.M., et al., Virology 306(1):162-169 (2003).|Le Roux, L.G., et al., J. Virol. 77(4):2330-2337 (2003).|Limon, A., et al., J. Virol. 76(21):10598-10607 (2002).|Dvorin, J.D., et al., J. Virol. 76(23):12087-12096 (2002).
USBio References
No references available
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