Technical Data

043135
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_000104.1; O14656
Gene ID
1861
Gene #
TOR1A
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TOR1A, CT (TOR1A, DQ2, DYT1, Torsin-1A, Dystonia 1 protein, Torsin family 1 member A)
TOR1A, DQ2, DYT1, Torsin-1A, Dystonia 1 protein, Torsin family 1 member A

The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1. [provided by RefSeq].

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TOR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the C-terminal region of human TOR1A.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Sharma, N., et al. Mov. Disord. 25(13):2183-2187(2010)|Kaiser, F.J., et al. Ann. Neurol. 68(4):554-559(2010)|Gavarini, S., et al. Ann. Neurol. 68(4):549-553(2010)|Granata, A., et al. Eur. J. Neurol. 17 SUPPL 1, 81-87 (2010) :|Warner, T.T., et al. Biochem. Soc. Trans. 38(2):452-456(2010)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net