043159
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_998839.1;Gene ID
7169Gene #
TPM2Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-TPM2, CT (TPM2, TMSB, Tropomyosin beta chain, Beta-tropomyosin, Tropomyosin-2)
TPM2, TMSB, Tropomyosin beta chain, Beta-tropomyosin, Tropomyosin-2
This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TPM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-280 amino acids from the C-terminal region of human TPM2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Martins-de-Souza, D., et al. J Psychiatr Res 44(14):989-991(2010)|Assinder, S.J., et al. Mol. Carcinog. 49(6):525-531(2010)|Ochala, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(21):9807-9812(2010)|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)USBio References
No references available