Technical Data

043196
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Gene ID
6399
Gene #
TRAPPC2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TRAPPC2, NT (TRAPPC2, SEDL, Trafficking protein particle complex subunit 2, Sedlin)
TRAPPC2, SEDL, Trafficking protein particle complex subunit 2, Sedlin

TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TRAPPC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human TRAPPC2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Liu, X., et al. J. Cell. Biochem. 109(6):1129-1133(2010)|Jeyabalan, J., et al. PLoS ONE 5 (5), E10646 (2010) :|Xia, X.Y., et al. Clin. Chim. Acta 410 (1-2), 39-42 (2009) :|Guo, H., et al. J. Genet. 88(1):87-91(2009)|Xiong, F., et al. Eur. J. Hum. Genet. 17(4):510-516(2009)
USBio References
No references available
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