Technical Data

043323
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
DB E
Crossreactivity
Hu
Accession #
NP_000359.1
Gene ID
7248
Gene #
TSC1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TSC1, phosphorylated (S598) (TSC1, KIAA0243, TSC, Hamartin, Tuberous sclerosis 1 protein)
TSC1, KIAA0243, TSC, Hamartin, Tuberous sclerosis 1 protein

This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.

Applications
Suitable for use in Dot Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Dot blot 1:500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S598 of human TSC1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Hoogeveen-Westerveld, M., et al. Biochim. Biophys. Acta 1802(9):774-781(2010)|Mehta, M.S., et al. Breast Cancer Res. Treat. (2010) In press :|Mieulet, V., et al. Trends Mol Med 16(7):329-335(2010)|Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)|Guo, L., et al. Acta Biochim. Biophys. Sin. (Shanghai) 42(4):266-273(2010)
USBio References
No references available
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