Technical Data

043358
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001166167.1; NP_005717.3
Gene ID
10102
Gene #
TSFM
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TSFM, CT (TSFM, Elongation factor Ts, mitochondrial)
TSFM, Elongation factor Ts, mitochondrial

This gene encodes a mitochondrial translation elongation factor. The encoded protein is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TSFM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-282 amino acids from the C-terminal region of human TSFM.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Wang, W., et al. Nucleic Acids Res. (2010) In press :|Smeitink, J.A., et al. Am. J. Hum. Genet. 79(5):869-877(2006)|Antonicka, H., et al. Hum. Mol. Genet. 15(11):1835-1846(2006)|Vernon, J.L., et al. Cytogenet. Cell Genet. 89 (3-4), 145-146 (2000) :|Xin, H., et al. J. Biol. Chem. 270(29):17243-17249(1995)
USBio References
No references available
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