Technical Data

043377
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu Mo
Accession #
NP_005715.1
Gene ID
10099
Gene #
TSPAN3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TSPAN3, ID (TSPAN3, TM4SF8, Tetraspanin-3, Tetraspanin TM4-A, Transmembrane 4 superfamily member 8)
TSPAN3, TM4SF8, Tetraspanin-3, Tetraspanin TM4-A, Transmembrane 4 superfamily member 8

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry and ELISA. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 90-117 in the central region of human TSPAN3. Species Sequence Homology: bovine
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human TSPAN3. Species Crossreactivity: mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Berditchevski, F. J. Cell. Sci. 114 (PT 23), 4143-4151 (2001) : 2. Todd, S.C., et al. Biochim. Biophys. Acta 1399(1):101-104(1998) 3. Wu, Y.J., et al. J. Biol. Chem. 266(26):17566-17572(1991)
USBio References
No references available
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