Technical Data

043406
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Accession #
NP_775771.3
Gene ID
146057
Gene #
TTBK2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-TTBK2, NT (TTBK2, KIAA0847, Tau-tubulin kinase 2)
TTBK2, KIAA0847, Tau-tubulin kinase 2

This gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TTBK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-253 amino acids from the N-terminal region of human TTBK2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Xu, Q., et al. Neurol. Sci. 31(1):107-109(2010)|Edener, U., et al. J. Neurol. 256(11):1856-1859(2009)|Houlden, H., et al. Nat. Genet. 39(12):1434-1436(2007)|Kitano-Takahashi, M., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 63 (PT 7), 602-604 (2007) :
USBio References
No references available
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