043585
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_066962.2Gene ID
7363Gene #
UGT2B4Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-UGT2B4, NT (UGT2B4, UGT2B11, UDP-glucuronosyltransferase 2B4, HLUG25, Hyodeoxycholic acid-specific UDPGT, UDPGTh-1)
UGT2B4, UGT2B11, UDP-glucuronosyltransferase 2B4, HLUG25, Hyodeoxycholic acid-specific UDPGT, UDPGTh-1
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
UGT2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of human UGT2B4.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Levesque, E., et al. Pharmacogenet. Genomics 20(3):195-210(2010)|Yong, M., et al. Cancer Epidemiol. Biomarkers Prev. 19(2):537-546(2010)|Li, J., et al. Breast Cancer Res. 12 (2), R19 (2010) :|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)USBio References
No references available