Technical Data

043603
Clone Type
Polyclonal
Host
Rabbit
Source
Mouse
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Mo
Accession #
NP_001092906.1
Gene ID
25989
Gene #
ULK3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ULK3, CT (ULK3, Serine/threonine-protein kinase ULK3, Unc-51-like kinase 3)
ULK3, Serine/threonine-protein kinase ULK3, Unc-51-like kinase 3

Serine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. May exert this function by promoting GLI1 nuclear localization. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ULK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the C-terminal region of human ULK3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Maloverjan, A., et al. J. Biol. Chem. 285(39):30079-30090(2010)|Takeuchi, F., et al. Circulation 121(21):2302-2309(2010)|Maloverjan, A., et al. Exp. Cell Res. 316(4):627-637(2010)|Levy, D., et al. Nat. Genet. 41(6):677-687(2009)|Kim, D.H., et al. Blood 113(11):2517-2525(2009)
USBio References
No references available
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