043610
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_061141.2; NP_001034764.1Gene ID
55898Gene #
UNC45AShipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-UNC45A, NT (UNC45A, SMAP1, Protein unc-45 homolog A, GCUNC-45, Smooth muscle cell-associated protein 1)
UNC45A, SMAP1, Protein unc-45 homolog A, GCUNC-45, Smooth muscle cell-associated protein 1
UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]).
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
UNC45A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the N-terminal region of human UNC45A.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Chadli, A., et al. J. Biol. Chem. 283(15):9509-9512(2008)|Bazzaro, M., et al. Am. J. Pathol. 171(5):1640-1649(2007)|Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :|Olsen, J.V., et al. Cell 127(3):635-648(2006)|Olsen, J.V., et al. Cell 127(3):635-648(2006)USBio References
No references available