Technical Data

043635
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_085047.1
Gene ID
80761
Gene #
UPK3B
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-UPK3B, ID (UPK3B, Uroplakin-3b, Uroplakin IIIb, p35)
UPK3B, Uroplakin-3b, Uroplakin IIIb, p35

UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]).[supplied by OMIM].

Applications
Suitable for use in Western Blot and ELISA. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 192-219 in the central region of human UPK3B, UniProt Accession #Q9BT76.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human UPK3B.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Foot, N.J., et al. Blood 112(10):4268-4275(2008) 2. Lamesch, P., et al. Genomics 89(3):307-315(2007) 3. Garcia-Espana, A., et al. Mol. Phylogenet. Evol. 41(2):355-367(2006) 4. Deng, F.M., et al. J. Cell Biol. 159(4):685-694(2002)
USBio References
No references available
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