Technical Data

043795
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Gene ID
7448
Gene #
VTN
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-VTN, NT (VTN, Vitronectin, S-protein, Serum-spreading factor, V75, Vitronectin V65 subunit, Vitronectin V10 subunit, Somatomedin-B)
VTN, Vitronectin, S-protein, Serum-spreading factor, V75, Vitronectin V65 subunit, Vitronectin V10 subunit, Somatomedin-B

VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

Applications
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Indirect Flow Cytometry. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:2000 Immunohistochemistry (FFPE): 1:10-1:50 Indirect Flow Cytometry: 1:25 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 65-93 in the N-terminal region of human VTN
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human VTN.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Jenne D.E., Stanley K.K.EMBO J. 4:3153-3157(1985) 2. Sigurdardottir O., Wiman B.Biochim. Acta 1208:104-110(1994) Seiffert D., Loskutoff D.J.J. Biol. Chem. 266:2824-2830(1991)
USBio References
No references available
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