Technical Data

043932
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
O43543; NP_005422.1
Gene ID
7516
Gene #
XRCC2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-XRCC2, NT (XRCC2, DNA repair protein XRCC2, X-ray repair cross-complementing protein 2)
XRCC2, DNA repair protein XRCC2, X-ray repair cross-complementing protein 2

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
XRCC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human XRCC2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Liu, Y., et al. Carcinogenesis 31(10):1762-1769(2010)|Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)|Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)|Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :|Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010)
USBio References
No references available
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