Technical Data

043974
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_003394.1
Gene ID
7528
Gene #
YY1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-YY1, ID (YY1, INO80S, Transcriptional repressor protein YY1, Delta transcription factor, INO80 complex subunit S, NF-E1, Yin and yang 1)
YY1, INO80S, Transcriptional repressor protein YY1, Delta transcription factor, INO80 complex subunit S, NF-E1, Yin and yang 1

YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
YY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of human YY1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Yu, H., et al. Mol. Cell. Biol. 30(21):5071-5085(2010)|Buira, S.P., et al. J. Neurochem. 115(1):283-295(2010)|Aoyama, T., et al. J. Biol. Chem. 285(39):29842-29850(2010)|de Nigris, F., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):14484-14489(2010)|Inayoshi, Y., et al. J. Virol. 84(16):8250-8261(2010)
USBio References
No references available
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