Technical Data

043997-APC
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Conjugate
APC
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA WB
Crossreactivity
Hu
Accession #
NP_055198.1
Gene ID
27033
Gene #
ZBTB32
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Rabbit Anti-ZBTB32, NT (ZBTB32, FAZF, TZFP, ZNF538, Zinc finger and BTB domain-containing protein 32, FANCC-interacting protein, Fanconi anemia zinc finger protein, Testis zinc finger protein, Zinc finger protein 538) (APC)
ZBTB32, FAZF, TZFP, ZNF538, Zinc finger and BTB domain-containing protein 32, FANCC-interacting protein, Fanconi anemia zinc finger protein, Testis zinc finger protein, Zinc finger protein 538

ZBTB32 is a DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T cells (By similarity).

Applications
Suitable for use in Western Blot and FLISA. Other applications have not been tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 96-125 in the N-terminal region of human ZBTB32.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human ZBTB32.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Stogios, P.J., et al. J. Mol. Biol. 400(5):983-997(2010) 2. Kaufmann, S., et al. J. Gen. Virol. 91 (PT 6), 1494-1502 (2010) : 3. Xin, X., et al. Genome Res. 19(7):1262-1269(2009) 4. Cohn, M.A., et al. Mol. Cell 28(5):786-797(2007) 5. Ikeda, R., et al. J. Cell. Biochem. 101(1):147-154(2007)
USBio References
No references available
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