Technical Data

044027
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_776159.1
Gene ID
170261
Gene #
ZCCHC12
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ZCCHC12, CT (ZCCHC12, SIZN1, Zinc finger CCHC domain-containing protein 12, Smad-interacting zinc finger protein 1)
ZCCHC12, SIZN1, Zinc finger CCHC domain-containing protein 12, Smad-interacting zinc finger protein 1

Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression (By similarity).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ZCCHC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 373-402 amino acids from the C-terminal region of human ZCCHC12.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Cho, G., et al. J. Biol. Chem. 284(29):19592-19600(2009)|Li, H., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(7):535-544(2009)|Cho, G., et al. Am. J. Med. Genet. A 146A (20), 2644-2650 (2008) :|Cho, G., et al. Mol. Cell. Biol. 28(5):1565-1572(2008)|Lamesch, P., et al. Genomics 89(3):307-315(2007)
USBio References
No references available
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